Volume 17, Issue 11 (1-2018)                   Modares Mechanical Engineering 2018, 17(11): 125-132 | Back to browse issues page

‎ 20.1001.1.10275940.1396.17.11.55.5

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Asgari H, Ta’atizadeh E, Sefidgr M, Soltani M. Simulation of oxygen pressure and nanoparticle FMISO concentration in tissue by considering a real capillary network. Modares Mechanical Engineering 2018; 17 (11) :125-132
URL: http://mme.modares.ac.ir/article-15-12377-en.html
Simulation of oxygen pressure and nanoparticle FMISO concentration in tissue by considering a real capillary network
Haniye Asgari1 , Erfan Ta’atizadeh1 , Mostafa Sefidgr * , Madjid Soltani1
1- Mechanical engineering, K. N. Toosi University of Technology, Tehran, Iran
Abstract:   (3931 Views)
Today by usage of the simulation of normal tissue and the process of material diffusion in body, the place of tumor can be predicted. By considering the tumor tissue, its growth can be evaluated. The fluid flow in the capillary, its effects on the adjacent tissue and the diffusion of molecules from capillary wall are considered in these kinds of simulation. Cancer cells due to the high rate of dividing cells, have a low level of oxygen. This lack of oxygen is called Hypoxia, so by using of different invasive and noninvasive manners, the amount of oxygen is measured in the body. The PET device indicates the oxygen distribution by use of special tracers in the several parts of body. In this essay by considering a real capillary network, the blood flow had been simulated, then by taking to the account of its effects on the tissue, oxygen pressure and the concentration of tracer had been simulated at the same time. At the end, the concentration of free and bind tracer is shown and its changes by the time is analyzed.
Keywords: Tumor, Hypoxy, PET, Oxygen pressure, FMISO
Full-Text [PDF 1254 kb]   (5169 Downloads)    
Article Type: Research Article | Subject: Biomechanics
Received: 2017/08/25 | Accepted: 2017/09/24 | Published: 2017/11/10
Add your comments about this article : Your username or Email:
CAPTCHA
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.