Volume 16, Issue 11 (1-2017)                   Modares Mechanical Engineering 2017, 16(11): 92-102 | Back to browse issues page

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Salari A, Sharifi A, Niazmand H. Iron-carbon micro particles drug targeting simulation in vertebrobasilar system: magnetic field effects. Modares Mechanical Engineering 2017; 16 (11) :92-102
URL: http://mme.modares.ac.ir/article-15-9404-en.html
Iron-carbon micro particles drug targeting simulation in vertebrobasilar system: magnetic field effects
Ali Salari1 , Alireza Sharifi1 , Hamid Niazmand *
1- Ferdowsi University of Mashhad
Abstract:   (4537 Views)
Injection drug micro particles into arteries is one of the stenosis treatments. Micro particles scattered in blood flow collide with plaques, drug is absorbed to treat stenosis. Since the collision of drug particles with artery wall depends on blood flow pattern, the efficiency of this method relies on guiding drug particles to stenosed site, otherwise the patient must take much higher drug dosage which has various side effects. Applying magnetic field and guiding drug particles to the target area extensively increases efficiency of the treatment and cuts side effects. In the present study, efficiency of using drug particles in vertebrobasilar system to treat atherosclerosis with and without applying magnetic field has been investigated. Ansys-Fluent commercial software has been used for numerical simulation. Results indicate applying magnetic field plays an important role in drug particles circulation as drug captivation surges almost 16 times. Injecting location and the particle diameters also have been examined and found to be important in the treatment effectiveness.
Keywords: Vertebrobasilar system, Vertebral Artery, Atherosclerosis, Magnetic Field, Magnetic micro particles
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Article Type: Research Article | Subject: Biomechanics
Received: 2016/08/23 | Accepted: 2016/10/4 | Published: 2016/10/26
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