TY - JOUR T1 - Investigating Stress Urinary Incontinence in Women Using Computational Methods and Clinical Data TT - بررسی بی‌اختیاری استرسی ادرار در زنان با استفاده از روش‌های محاسباتی و داده‌های بالینی JF - mdrsjrns JO - mdrsjrns VL - 17 IS - 5 UR - http://mme.modares.ac.ir/article-15-707-en.html Y1 - 2017 SP - 419 EP - 429 KW - Computational Fluid Dynamics‎ KW - ‎Fluid Structure Interaction‎ KW - ‎Finite Element Method‎ KW - ‎Urinary System‎ KW - ‎Stress Urinary Incontinence N2 - Stress urinary incontinence (SUI) is characterized by the involuntary transurethral leakage of urine caused by an increase in abdominal pressure in the lack of an adequate bladder‎ ‎contraction that raises the vesical pressure to a level that exceeds urethral pressure‎. ‎Adult women are most commonly affected by SUI which is believed to be caused in part by‎ ‎injuries to the pelvic floor sustained during childbirth‎. ‎Despite the large number of women affected by SUI‎, ‎little is known about the mechanisms associated with the maintenance of urinary continence in women‎. ‎The work in this ‎research ‎focuses on studying the behavior of the bladder and the dynamics of the urine during an increase in abdominal pressure like a cough‎. ‎The computational model is developed by using the Finite Elements Method (FEM) and Fluid-structure interaction (FSI) techniques. ‎The results show a good accordance between the clinical data and predicted values of the computational models. ‎Simulated pressure is more accurate in the model in which non-linear material properties are utilized. The results of the computational methods indicate that by using numerical techniques and simplification of the physics of biological systems, clinical results can be reached in virtual environments in order to understand pathological mechanisms. M3 ER -