The development of built environment and increase of energy source utilization have led to paying attention to different procedures to optimized energy consumption in buildings. Designing different sort of double skin façade provides opportunities to keep building in more balanced environment and use less energy to provide comfort condition. As a natural process that optimizes energy consumption by balancing between different solutions, homeostasis is used as a pattern in designing this sort of homeostatic façade. Nowadays, different sorts of smart façade have been used on the boundary of building and environment. A sort of smart façade, which is designed based on homeostatic process, is able to create a sustainable balance between different solutions, adapting to environmental changes, and define the hierarchy of their use in different conditions, so as to provide thermal comfort conditions inside the building with higher efficiency than conventional smart façades. In this study, temperature fluctuation limits in homeostatic façade is determined and solutions are derived from a natural homeostasis system, and used in the design of the desired façade. The aim of this research is to compare the efficiency of temperature reduction solutions in different conditions and specified optimal one. For this end, a modulus of homeostatic façade is built and the operation under laboratory condition is evaluated, and also its behavioral relationship is examined with temperature fluctuations.