مهندسی مکانیک مدرس

مهندسی مکانیک مدرس

ساخت داربست های استخوانی با روش ساخت افزایشی ریزش مذاب و بررسی خواص مکانیکی آنها

نوع مقاله : پژوهشی اصیل

نویسندگان
عاطف نجفی 1
عباس ذوالفقاری 2
1 دانشجوی کارشناسی ارشد، مهندسی مکانیک، دانشگاه صنعتی نوشیروانی بابل، بابل
2 استادیار گروه ساخت و تولید، دانشکده مهندسی مکانیک، دانشگاه صنعتی نوشیروانی بابل
10.52547/mme.23.1.1
چکیده
بهره ­گیری از تکنیک­های ساخت افزایشی در علم پزشکی موجب تحولی عظیم در این زمینه و به ­خصوص در حیطه مهندسی بافت استخوان شده است. یکی از این تکنیک­ها، فرآیند ساخت افزایشی ریزش مذاب می ­باشد که برای ساخت داربست­های استخوانی استفاده می­گردد. از دیدگاه مهندسی بافت استخوان، داربست­های استخوانی باید علاوه بر ویژگی­های مورد نیاز بیولوژیکی، دارای خواص مکانیکی قابل قبولی نیز باشند. در این پژوهش ابتدا پارامترهای چاپ شامل ارتفاع لایه، سرعت چاپ و تعداد فیلامنت در هر ردیف تعیین شد. داربست­های استخوانی با 2 ماده مختلف پلی لاکتیک اسید (PLA) و پلی کاپرولاکتون (PCL) ساخته شد و تحت آزمونهای فشاری قرار گرفتند. نتایج تحلیل شده شامل مدول الاستیک و تنش تسلیم با نرم ­افزار Design Expert نشان دهنده ­ی آن بود که افزایش ارتفاع لایه موجب کاهش خواص مکانیکی و افزایش تعداد فیلامنت در هر ردیف باعث افزایش خواص مکانیکی داربست ساخته شده می­گردد. به عنوان مثال برای داربست­های ساخته شده از جنس PLA، حداکثر مدول الاستیک متعلق به داربست 12 فیلامنتی با ارتفاع لایه 1/0 می­باشد که مقدار آن برابر با 319 مگاپاسکال بوده و حداقل مدول الاستیک متعلق به داربست 8 فیلامنتی با ارتفاع لایه 3/0 می­باشد که مقدار آن برابر با 143 مگاپاسکال است. سرعت چاپ برای داربست­های ساخته شده از جنس PLA، تاثیرقابل توجهی بر مدول الاستیک و تنش تسلیم نداشته ولی برای داربست­های ساخته شده از جنس PCL، افزایش سرعت چاپ موجب کاهش مدول الاستیک می­شود ولی اثر قابل توجهی بر تنش تسلیم ندارد.
کلیدواژه‌ها
ساخت افزایشی
داربست استخوانی
پارامترهای چاپ
تست فشار
خواص مکانیکی

موضوعات

عنوان مقاله English

Fabrication of bone scaffolds by additive manufacturing of fused deposition modeling (FDM) and investigation of their mechanical properties

نویسندگان English

Atef Najafi 1
Abbas Zolfaghari 2
1 Master's student, Mechanical Engineering, Noshirvani University of Technology, Babol, Babol
2 Assistant professor of manufacturing department, faculty of mechanical engineering, Babol Noshirvani University of Technology
چکیده English

The use of Additive Manufacturing (AM) techniques in medical science has resulted in a great change in this field, especially in bone tissue engineering. One of these techniques is the Fused Deposition Modeling (FDM) which is used to make bone scaffolds. From view point of bone tissue engineering, bone scaffolds must have acceptable mechanical properties in addition to the required biological properties. In this study, at first the printing parameters including layer height, printing speed and number of filaments in each row were determined and bone scaffolds were made with two different materials polylactic acid (PLA) and polycaprolactone (PCL) and were subjected to the compression tests. The results of Young’s modulus and yield stress analyzed in Design Expert software showed that increasing the layer height reduces the mechanical properties. Also, increasing the number of filaments in each row increases the elastic modulus of the scaffold. For example, for scaffolds made of PLA, the maximum modulus of elasticity belongs to 12 filament scaffolds with a layer height of 0.1, which is equal to 319 MPa, and the minimum elastic modulus belongs to 8 filament scaffolds with a layer height of 0.3, which is equal to 143 MPa. Printing speed for scaffolds made of PLA does not have a significant effect on the Young’s modulus and yield stress. But for scaffolds made of PCL, increasing the printing speed reduces the modulus of elasticity but it doesn’t have a significant effect on yield stress.

کلیدواژه‌ها English

Additive Manufacturing
Bone scaffold
Printing Parameters
Compression test
Mechanical properties
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مهندسی مکانیک مدرس
دوره 23، شماره 1
دی 1401
صفحه 1-9