In this research behavior of bubble due to under water explosion and it’s effects on ship structure have been studied. For determination of these effects field equations must be derived and solved them by mathematical simulation. Mathematical model is com in follow, it show physical rules on impression of bubble oscillation on body ship. This model is solved by combination of Euler method, 5 step Adams-Beshforse method and 4 step Adams-Moltone method for explaining the response of ship structure due to oscillation bubble. In order to agreement of solution way, stress-strain curves that obtained in this paper, is compared with experimental results. Also this results compared with FEMA results. Ship structure is modeled in ANSYS software in free beam form with variable mass and stiffness elements. Internal ship’s equipments and buoyancy are modeled by local mass and spring. The effect of explosion depth and explosive mass on stress in ship structure is studied. These result show when explosion depth is increased, stress is decreased and when explosive mass is increased, stress is increased.