Thoughts Kierkegaard, one of the leading pioneers of existentialist philosophy, has greatly influenced Sartre's existentialist ideas and his literary and theatrical works and prominent filmmakers in the history of world cinema and other artists in other fields. In this article, organized in three parts, we aim to examine the reflection of Thoughts Kierkegaard's on categories such as "truth, forgetfulness, domination of popular beliefs, existential and non-existent human beings, individualization and liberation from Intermediate, and freedom and Selection." Sepehr Hasti and ... " are among the factors that Sartre's literary works are completely influenced by and in artistic forms and forms and the form of images and dramatic phenomena in dramatic and literary works, Sartre's screenplays are skillfully, creatively, and attractively reflected. Has found. In the form of fascinating visual events, stories, and adventures, these phenomena have woven and implemented the abstract ideas of existentialism in such a way that its created characters, as if living in their natural life and in a completely real way, disappear. Sartre's plays The Flies, a historical work adapted from the Greek playwright Euripides, The Noble Prostitute, the subject of contemporary American society, and The Infected Gangs, whose adventures and events take place. Concerned with World War II and the French resistance movement, it has received the most influence from Kierkegaard's philosophical thought. In this article, we have shown the extent of Sartre's influence on Kierkegaard by examining these plays.
 

Aims: Locus of control (LOC) refers to the extent to which individuals believe that they can control events that affect them. Health Locus of Control (HLOC) refers to beliefs that related to how one’s health is affected by oneself, others, or fate; and also it is one of the most broadly measured factors of health beliefs for the scheduling of health education programs. The aim of this study was to assess HLOC among Students at Isfahan University of Medical Sciences.
Materials and Methods: This cross‑sectional study was conducted in 297 students in Isfahan University of Medical Sciences in Iran selected by simple random sampling method in 2018. Data collection was done by the demographic questionnaire and Form “B” of Multidimensional Health Locus of Control (MHLC) scale. Statistical analysis includes (ANOVA, t-test, Pearson test) was performed using SPSS version 20 and p<0.05 was considered statistically significant.
Findings: The mean±SD of three dimensions of HLOC were 26.41±3.98, 16.64±4.36 and 21.67±4.37 for internal, chance and powerful others respectively. There was a significant relationship between internal and powerful others locus of control dimensions with sex (p=0.035, p=0.041). Further, there was not a significant relationship between HLOC dimensions with students’ age, major, parent’s education and occupation.
Conclusion: Since the most scores were relating to an internal locus of control dimension and fewer scores were relating to the chance locus of control dimension, it can be concluded that personal behavioral factors have more influence on students' health and their beliefs about chance, luck or fate has less influence on their health.

The aim of this study is to investigate the life-span according to the damage caused by the main mechanisms of damage development in turbine blades and to model the growth of the damage. For this purpose, the low cycle fatigue test on martensitic 410 stainless steel was immersed in tempered glass at 565°C in three strain gauges 0.8, 1 and 1.5 with a constant temperature of 500°C and 15 seconds per cycle. The effect of creep-fatigue interaction on life and also damage to turbine blade in different conditions was investigated. The results showed that with the variation of the strain amplitude from 0.8 to 1.5, the life of the piece varies from 205 to 65 cycles and this is while the level of failure of the samples varies. In the next step, the modified Coffin-Manson model was used to indicate the damage and its simultaneous effect on the life of the piece. The results showed that decreasing the number of grain boundaries and its effect on the cavities created in the piece decreases the damage and thus the life of the turbine blade increases. High-temperature tensile tests and low-tensile fatigue-temperature control were also performed in different tempering modes for 410 and 420 steel stainless steel and The results showed that, under the same conditions, the temperature increase from 200 to 565°C resulted in a decrease in life from 2218 to 1952 cycles.

Today, the use of ultrasonic waves is expanding to the separation of particles or cells. One of the effective factors in the separating is cell deformation caused by ultrasonic waves. The most popular models used for deformation are the elastic and viscoelastic models. In this research, the cell has been modeled in a fluid environment under the influence of ultrasonic waves and deformations has been obtained. For this purpose, the Helmholtz equation that is a combine of the disturbance equations of sound waves and Navier-Stokes equation is solved and acoustic pressure is obtained. This pressure is then applied to the cell as deformation agent and the deformation is obtained using fluid-solid interactions modeling. Initially, deformation of the cell with elastic properties has been presented and validation has been conducted using comparison with the previous experimental researches. Finally, the deformation for the viscoelastic cell, which has so far not been used for deformation modeling in the acoustic field, has been obtained and presented. The results show that the viscoelastic model has the most compatibility with the experiment results. Also, the effect of frequency on the aspect ratio has been investigated. As the frequency ranges increased from 2 to 8 MHz, the aspect ratio is increased to 0.3.

Aims: Botulinum neurotoxins are the strongest known bacterial toxins that cause muscle paralysis due to inhibition of acetylcholine release. Design of inhibitors is still pursued as a major strategy for intracellular inhibition of poisoning caused by these toxins. Investigation of the potential function of design inhibitors, pure poison or catalytic area is essential. The aims of present study were expression and purification of recombinant catalytic domain of botulinum neurotoxin type E (BoNT/E) Type E from a synthetic gene.
Materials and Methods: In this experimental study, the sequence of the botulinum neurotoxin type E light chain was adopted from GeneBank and codons were optimized according to E.coli BL21 (DE3) codon usage. Other bioinformatics tools were exploited to reach the optimum expression of the gene in the mentioned host. The resultant (gene) was then ordered to synthesize and cloning in pET28a (+) expression vector. The recombinant vector was transferred into E. coli BL21 (DE3) host cells. The expression of the protein was induced by addition of IPTG. The expression conditions were changed to obtain a soluble expression of the protein. Then, the protein was purified by an affinity chromatography, followed by a further purification with amicon filter. SDS-PAGE was used to evaluate expression and purification of the protein and Western blotting was performed to confirm the expressed protein.
Finding: Codon Adaptation Index of the gene increased to 0.85. The third predicted structure showed good quality. The thermodynamic analysis of the mRNA structure showed that the predicted structure is stable. The soluble expression was obtained in 18°C and 18h induction by 1 mM IPTG. Protein production with higher more than 90% purity was confirmed.
Conclusion: Optimization of the protein expression conditions resulted in producing the solution in the culture medium by E. coli BL21 as host.