Waste heat recovery systems, which make use of waste sources for their input energy, have considerable importance in industry since they utilize streams, which will be disposed to nature if not employed. Ship’s engines are one of the places, where a large amount of energy is wasted in different forms. In the present article, the idea of making use of these loss streams and consequently producing useful power in the outlet is proposed in the form of two systems. In the first system, the only stream of exhaust gases is utilized, while in the second system, the jacket cooling water is used together with the engine exhaust gases. Screening in the working fluids is conducted in order to select appropriate fluids, which have suitable characteristics in the physical, safety, and environmental aspects. The analyses indicate that using R600a presents the highest net power output, which reaches to the value of about 575 kW at the most. Comparison of the two introduced systems shows that preheating the working fluid by the jacket cooling water makes the better operation of the system and the power output is increased up to about 31-58% in different fluids. The lowest payback period in the systems is achieved through the use of R600a as the working fluid, which is about 3.48 year in the second system.