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Pashto language is one of the Iranian languages about which little linguistic research has been conducted. Causation in Pashtu language needs more explanation because this issue is very important, but in Pashto grammar books and linguistics, no attention has been paid to this issue. Therefore, the investigation and research of causation in this language is of particular importance. The purpose of this research is to describe the causative category of Pashto language. the data required for this research is based on the works and speakers of this language based on the research of Dabir Moghaddam (1399). In addition to the description of causation, the research method of this article is based on Pashto language examples that have been transliterated and interpreted. Examples of this text have been selected from hundreds of sentences and analyzed. The important issue is the representation of causative construction in Pashto language, and how it is done. Pashto language is one of subject-object -verb languages and causation exists in this language in the form of morphology and syntax. This research has analyzed the data based on the taxonomy theory. Language causation in Pashto is more complicated than in Persian; because it does not follow a specific principle. In causative conjugation, in addition to (aw) affix, prefixes (pӘ,pӘr) and (war bânde,pre) are used. The rate of generation of auxiliary causatives is higher in Pashto language because it comes with most verbs and makes the verb transitive.
 

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Today, the news media has a momentous role in shaping public opinion and social developments. Journalistic translation thus follows guidelines and standards in order to convey the message and objectives of its source material. The translation of the political press discourse surrounding the US and international sanctions on Iran is particularly sensitive, due to its high potential in impacting international relations and political affairs.
The objective of our research is to highlight the importance of methodologies used for the translation of political press discourse. For this purpose, we have analyzed two important news articles related to the aforementioned sanctions. First, we conduct a critical analysis of the political discourse, based on Van Dijk's model, and then we perform a translational analysis, based on Antoine Berman's views. Finally, we explore the different types of modifications made by translators, as well as the efforts made to adapt the news to the media’s political ideology. In line with Van Dijk's opinions, we have shown that there is a close relationship between the ruling policy (power) and the press discourse (media), in shaping the public perception of policies and events at mass scale. We demonstrate how subtle deletion, change, and intensification is strategically used in jo urnalistic translation, in line with their desired discourse functions to achieve political goals.
 

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Explaining the nature of metaphor and its role in language has always been a controversial topic in the fields of linguistics, philosophy of language, rhetoric, and so forth. In metaphor analysis, these fields often converge in an inseparable manner. Donald Davidson, a 20th-century philosopher, is one of the influential theorists in the Philosophy of Language and the Theory of Meaning. His views on the essence and role of metaphor in language bear significant similarities to the ideas of  al-Jurjani, a prominent 5th-century Hijri literary scholar. This research aims, through a descriptive-analytical method and a comparative approach, to examine the intersection points of Davidson’s and al-Jurjani’s theories, with one addressing metaphor from a philosophical and linguistic perspective and the other from a rhetorical standpoint. For this purpose, Davidson’s essay "What Metaphors Mean?" is used as the basis for reviewing his theories on metaphor. Al-Jurjani’s views are analyzed with a focus on "Dala'il al-I'jaz." This study yields results in three areas. The first, identifies similar aspects in the two theories, indicating that both theorists reject the idea of metaphor being merely a shortened simile. They also critique the notion of "metaphorical meaning," emphasizing that the meaning of a metaphor cannot be reproduced in any form other than the metaphorical one itself. The second area involves finding complementary aspects in the two theories, considering Davidson's philosophical stance and al-Jurjani's rhetorical position. The third area elaborates on the connection between al-Jurjani's direct views on metaphor and the ideas indirectly inferred from theory of Construction.

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The present study aimed to examine the use of different levels of syntactic architecture in written personal and fictional narratives in both Persian and English across three discourse communities, namely Persian native speakers, English native speakers, and Iranian EFL learners. To this end, the participants of the study were selected based on convenience sampling and were asked to write one of their happiest memories. Also, an English fable from Aseop's fables and a Persian story, chosen based on comparative literature and having the similar plot, were given to them to read and write whatever they remembered; there was no limit on the number of words and paragraphs. To analyze the data, the Berman and Nir-Sagiv's (2009) model was followed. The findings showed that in fictional narratives written by both Persian and English native speakers, isotaxis, asymmetric parataxis, complement (CMP), and parataxis levels were frequently employed; however, personal narratives in Persian were dominantly isotactic, paratactic, and asymmetric paratactic, CMP, while isotactic, hypotactic, and paratactic levels were frequent in English written personal narratives. Also, after receiving explicit instruction on different types of English sentences, the use of adverbial and relative clauses (hypotaxis level) increased in Iranian EFL learners' written narratives. It can be concluded that explicit teaching of syntactic levels enabled EFL learners to arrange their sentences correctly to express their intended meaning. Teachers can benefit from the results to gain a more comprehensive understanding of narrative connectivity and help EFL learners elaborate clause linkage in their written narrative tasks.
 

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Urban growth boundaries are considered one of the key tools for controlling and managing the physical development of metropolitan areas. Uncontrolled and unplanned expansion in these regions has become a major challenge for urban and regional planners and managers, as this process leads to the destruction of agricultural lands and natural resources. The aim of this research is to simulate and assess future changes in growth boundaries in the Isfahan metropolitan area with the goal of preserving environmental resources and controlling physical expansion. In this regard, by adopting a positivist approach that follows an analytical and measurement-driven process, satellite imagery was utilized to assess changes in the physical expansion of the Isfahan metropolitan area. Artificial neural networks and machine learning algorithms were employed to predict the extent of future physical growth, and the projected growth boundaries were delineated. The research findings indicate that the Isfahan metropolitan area has experienced significant uncontrolled expansion, particularly in terms of physical development, over recent decades, and the reduction of agricultural and natural lands has become one of its major challenges. Based on the conducted simulations, the proposed growth boundaries can serve as an effective tool for managing and planning urban-regional development and preventing further degradation of natural resources and lands.

 

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Background: Differentiation ofmesenchymal stem cells (MSCs) to hepatocyte-like cells could be associated with development of liver function factors. The impact of differentiation-dependent changes on DNA integrity is not well understood. In this study, hepatocytes and their progenitor stem cells were treated with aflatoxin B1 (AFB1) and amplification of selected genes linked to DNA damage was examined. Methods: MSCs and CD34+ cells isolated from umbilical cord blood (UCB) were treated with AFB1 (0, 2.5, 10 and 20 µM) in selective media supporting the hepatocyte differentiation. After 24 htreatment the DNA damage (Comet assay) and amplification rates ofP53 and β-globin genes were measured using real time polymerase chain reaction (QPCR). Results:The results show that AFB1 treatments resulted in a concentration- dependent increase in the DNA damage and suppression of the specific gene amplification. The extent of DNA damage was significantly greater in hepatocytes differentiated from MSCs when compared to those obtained from CD34+ cells. The effects of AFB1 on the rate of selected gene amplification in QPCR showed that the lesions (expressed as lesions/10 kb) in P53 and β-globin genes was significantly greater in hepatocytes derived from MSCs as compared to the cells derived from CD34+ cells. Conclusions: These data together with the results of cytochrome P450 (CYP3A4) expression in the cells suggest that the non-differentiated stem cells are probably less vulnerable to genotoxic agents as compared to hepatocytes differentiated from them.

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Background and Objectives:HBV and HTLV-I are life threatening infectious agents in patients who receive blood and blood products. Although serological methods have been proved to be useful, detection of these viruses has remained a challengingissue due to the many obstacles. By the advent of Nucleic Acid Testing methods, especially in multiplex format, more precise detection is possible.The objective of this study was to develop a reliable, rapid and cost- effective method tosimultaneously detect HBV and HTLV-I. Materials and Methods: We have developed a multiplex Real time-PCR assay for simultaneous detection of HBV and HTLV-I. Primer sets were designed for highly conserved regions of genome of each virus. Using these primers and standard plasmids, we determined the limit of detection, clinical and analytical specificity and sensitivity of the assay. Monoplex and multiplex Real-time PCRs were performed. Results: Analytical sensitivity was considered to be 1000 and 100 copies/ml for HBV and HTLV-I, respectively. High concentration of one virus had no adverse effect on detection of t low concentrations of the other one. By analyzing 30 samples, clinical sensitivity of the assay was determined to be 87% and 96% for HBV and HTLV-I, respectively. Using different viral and human genome samples, the specificity of the assay was verified to be 100%. Conclusions:We have developed a reliable, rapid and cost effective method tosimultaneously detect HBV and HTLV-I.Our results indicatedthe high capability of this simple and rapid method for detecting these viruses in clinical samples.

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Background: Musculoskeletal disorders (MSD) represent one of the most frequently occurring and costly occupational issue in nursing. The nursing profession is one of the most stressful occupations today, because of the quantity and diversity of risk factors associated with the work environment. The aim of this study was to examine the relationship between burnout syndrome and musculoskeletal disorders. Material and Methods: In this cross-sectional study a questionnaire survey was carried out among 415 nursing personnel in five educational hospitals in Hamedan, Iran. Data were collected through two unnamed questionnaires including Maslach Burnout Inventory, Visual Analogue Scale (VAS). Results: Statistical analysis showed that the most commonly painful regions among the nurses were lower back (5.53%), left foot (5.08%), and head and neck (4.43%), right foot (4.90%), right knee (3.84%) and left knee (3.74%). The lowest pain, were found to be in right and left elbows (1.99%) and (1.91%), respectively. Also emotional exhaustion, depersonalization and personal accomplishment has significant correlation with musculoskeletal disorders (P = 0.000, r = 0.122). Conclusions: The results showed high prevalence of MDS among Iranian nurses that could be due to emotional exhaustion and depression.  

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The foreign policy of Saudi Arabia in the international system is, above all, the result of this country's competitive view of the Islamic Republic of Iran and security equations in the West Asian region. The present study, through documentary research and reflective analysis technique aims to explain how Saudi Arabia, in order to shape strategic depth, controls international waters, influences the political structure of African countries, and creates a stream of Salafi groups in Africa, and how it seeks to reduce Iran's power, pose a threat to Iran, and increase its offensive capacity. Saudi Arabia believes that Iran has a high offensive capability in the region and can easily become a country with aggressive and war-initiating power. By shaping the policy of expanding geopolitical and strategic depth, interventionism and dominating the cultural discourse of Saudi Arabia in Africa, it is trying to turn the security equations into acute security threats for the Islamic Republic with trans-regional balancing.
 

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The influence of leaf pubescence of three wheat cultivars (Pishtaz, Ghuds and Falat) on preference and biological parameters of Sipha maydis (Passerini) was investigated under greenhouse conditions (25 ± 2 °C, 70 ± 10% RH and 14: 10 h (L: D) photoperiod). The results showed that Pishtaz had a greater density of trichomes compared to the other cultivars. In the preference test with whole plant, the number of aphids on Pishtaz was significantly greater than that on other cultivars at 48 hrs after infestation. Similarly, in the preference test on leaves, the numbers of attracted aphids per leaf was highest on Pishtaz. In the life table study, there was no significant difference of intrinsic rate of natural increase (r_m) among the three studied cultivars but it was highest on Pishtaz (0.187 /day). Aphids’ net reproductive rate, doubling time, mean generation time and finite rate of increases did not show significant differences between the tested cultivars. According to our results, leaf surface pubescence of wheat is not an effective resistance mechanism against S. maydis.

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Problem statement: Today, the issue of thermal comfort has been raised as one of the important factors in the quality of urban open spaces along with physical factors. Basically, citizens tend to be in spaces where they feel thermally comfortable. Due to the effect of various parameters in urban open spaces that affect the thermal comfort of users and the lack of codified principles in this regard, the creation of such a space in an urban area has become difficult to identify and meet the thermal needs of city designers.
Results: Studies showed that in the open spaces of the urban environment, due to the influence of various factors, absolute thermal comfort conditions can not be achieved throughout the day; Rather, thermal comfort conditions are expected to be provided for certain hours. To improve thermal comfort in urban open spaces, elements such as vegetation, water, proper orientation, type of materials, color, activity rate and coverage rate are important. It is obvious that by using these factors and observing the time of presence in the open space of Rudkenar sidewalk, thermal comfort will be provided in it.
Method: The research is applied-developmental in terms of purpose; And is based on analytical method. In this method, in order to study the microclimate, the software simulation technique (Envi met) has been used as one of the most complete simulation software in the field of urban microclimate, and the values ​​of PMV thermal comfort index (average vote prediction) using simulation in different parts of the route The designed sidewalk that has different conditions and situations has been calculated and the changes of two factors of temperature and radiation and its effect on the thermal comfort of Khorramabad river in Lorestan in summer have been studied.
Conclusion: Finally, it was found that factors such as choice of direction, walking time, sidewalk width, the presence of trees and vegetation, shade and water, as well as some user characteristics such as metabolic rate and activity, coverage rate in terms of thermal comfort in this season of the year Has been impressive.
 

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Oxygen concentration the environment and cellular organisms is one of the effective factors during normal development of organisms. In the present study, the transcription levels of the hypoxia-inducible factors (hif-1, hif-2) were evaluated during development of an ancient fish species Acipenser persicus, in the normal oxygen density of environment. The transcription of hif-1, hif-2 detected in all developmental time-points defined, from embryo to juvenile stages. Target genes transcriptions were normalized using RPL6 as reference gene. Changes in normalized hif-1, hif-2 mRNA expression were statistically significant throughout developmental points (p<0.05). Our data revealed that the mRNA expression of hifs were low during embryonic development and then upregulated significantly at hatching and early larval time-points. Then, in the late larval development and juvenile stage the expression of hifs started to decline. The comparison between hif-1 and hif-2 mRNA transcription showed that maximum gene expressions of hif-1and hif-2 occurred in 15 and 20 days after hatching, respectively. The increased expression of hifs suggests their association with two important events in the larval evolution, viz. internal feeding (yolk absorption) and external feeding. Also, the observed increase in mRNA expression of hifs during larval development of A. persicus can be attributed to increase in oxygen demand.

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Label switching technology is a flexible and high performance method for forwarding layer three packets that are mapped to layer two flows. Each label switch router, LSR, needs a specific label for every flow, where the number of labels depends on the mapping and granularity of flows. Data and control driven methods are the most significant and popular methods in label mapping policy. The above mentioned methods have been investigated. The possible pitfalls of each method are identified for an optimal operation and performance. One of the most significant difficulties is the rate of flows creation and deletion. This issue is vital in both scalability and implementation of networks and is more significant in data driven methods. In this paper, a new flow-Subnet Flow-has been proposed which increases the performance in data driven methods. The simulation results show fair improvement in performance and validity of the Subnet Flow.

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Inheritance of several yield-based drought resistance indices was studied by a halfdiallel method using seven winter wheat varieties. The parental lines were such chosen as to represent a broad range of drought stress resistance. The experiment was conducted in a split-plot design at the research farm, Faculty of Agriculture, Zanjan University, Iran, in 1998. Irrigated vs. rainfed regimes were considered as the main plots. The F1 hybrids and parental varieties constituted the subplots. From the grain yield data, some drought resistance indices such as geometric mean productivity (GMP), mean productivity (MP), standard superiority measure (SP), stress susceptibility index (SSI), stress tolerance index (STI), superiority measure (P), and tolerance (TOL) were calculated. Genetic components of variance and heritabilities were estimated using Gardner and Eberhart’s Method 3, Model II. Significant differences among parents and F1s were observed for all indices except for SSI and TOL. Significant general combining abilities (GCA) were obtained for GMP, MP, P, SP, STI, and TOL but not for SSI. Therefore, except for SSI, other indices could be regarded as heritable. The specific combining ability (SCA) effects were also highly significant for GMP, MP, P, SP, and STI. However, additive variances were more important than dominance ones. Narrow-sense heritability estimates were very low for SSI, low for TOL, but moderate for GMP, MP, P. SP, and STI. Thus selection based on the latter indices could be more promising than on SSI and TOL. It seems that SP and STI might be better yield-based drought resistance indices to be employed in plant breeding programs, because of their moderate narrow-sense heritabilities and the inherent ability of selecting high yielding genotypes in either stressed or non-stressed conditions.

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The effect of cadmium on hematological and biochemical indices of silver carp (Hypophthalmichthys molitrix) exposed to subacute (0.65ppm) and acute (3.25ppm) concentrations for 96-h test period was assessed. The results showed that Hb, Hct, RBC and MCV significantly decreased in low concentration of cadmium (p<0/05), while MCH, MCHC, WBC, glucose and cortisol were significantly (p<0/05) higher than control group in both low and high concentrations. This study reveals that some hematological and biochemical indices of silver carp, such as cortisol, can be used as suitable biomarkers in tracing Cd²⁺ contamination within water bodies.

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RNAs play a fundamental role in many biological and medical processes and the activity of RNA is directly dependent to itsstructure. Designing RNA structures is a basic problem in biology that is important in the treatment and nanotechnology. In this regard, some algorithms have been formed to predict RNA secondary structure. In this paper, we present an algorithm to accurately predict RNA secondary structure based on minimum free energy and maximum number of adjacent base pairs. This algorithm stands on a heuristic approach, which employs a dot matrix representation of all possible base pairs in RNA. Afterward, stems are extracted from the dot matrix and decreasingly sorted based on their length. Then the stems with equal length are increasingly sorted according to the free energy. Finally, the stems are orderly selected to form RNA secondary structure. The proposed algorithm is performed on some datasets containing CopA, CopT, R1inv, R2inv, Tar, Tar*, DIS, IncRNA54, and RepZ in the bacteria. Experimental results showed high accuracy of 95.71% of the proposed algorithm. This algorithm is run in lower computational time in comparison to the other similar approaches.