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Well-being includes phenomena such as mental health, life satisfaction, positive attitude and feeling happiness. The present study deals with the relationship between language and well-being and claims that well-being factors are expressed in the words of the language. For example, the happiness factor in a language is reflected by certain words such as happy, happiness and satisfied. The theoretical framework of the present study is ecolinguistics. The method is corpus based. The data is extracted from the research of Secretariat of Emotional Intelligence of Tehran Education in 2017. In this study, the well-being status of 1095 high school students, the first and second period, girls and boys, public and private of District One of Tehran have been evaluated. The students' responses to the question about well-being criteria are the base of the present study. The corpus consists of 1161 words with a frequency of 35,455. The content words associated with the five Well-being factors of engagement (occupation and entertainment), perseverance, optimism, connectedness and happiness were extracted in the framework of the semantic map of Jiaqi Wu et al. (2017), by using top-down method. They were analyzed using Excel and SPSS soft-wares. Some examples of the words that represent the well-being factor of happiness are: “relaxation, facilities, happy, healthy, fun, health, happiness, excellent, pleasant, relaxed, happy, satisfied, faith, satisfaction, enjoyed, happiness, joy, and fun”. The research findings show 6845 words of the corpus (about35.7%) are related to well-being, and there is a significant relationship between well-being factors and produced words

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The present article aims to analyze six contemporary short stories based on Halliday and Matthiesen's systemic functional grammar framework (2014). In functional grammar, the message and textual meaning of clauses will not be revealed to the reader without identifying the topical themes and the discourse factors influencing to highlight them. Thus a perfect interpretation of the message will not be obtained. The study answers the question how the thematic structure in clauses helps highlight and convey the author's messages. The study hypothesis is: the thematic structure conveys the author's message by highlighting the topical themes by means of syntactic tools. the study corpus contains six contemporary short stories, comprising 3736 clauses. The descriptive- analytic method were used to analyze all the 3736 clauses based on thematic structure in textual metafunction.  The data analysis showed that in unmarked clauses the topical themes were used in their natural place as subjects, mostly being participants to preserve and maintain the topic. However, when there were good discourse reasons such as new events, topic change and certain meaning, mostly preposed adjuncts were used as topical themes in marked declarative clauses. while the process was used as topical theme in imperatives to show the participants social status. Therefore, the readers by using the thematic structure and identifying the topical themes can understand the author's intended textual meaning and his message in unmarked and marked clauses.
 

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A 12-week feeding trial was carried out in 500 L fiberglass tanks  to evaluate the effect of dietary choline at 0, 2, 4, and 8 g kg ^-1 levels on growth rate, body composition and total liver lipid of juvenile Acipenser baerii (37.67±0.67 g). A semi purified basal diet was formulated using vitamin free casein and wheat gluten as a protein source, a mixture of animal and plant oils as a lipid source and dextrin as a carbohydrate source. Four isonitrogenous (40% protein) and isoenergetic (18 MJ kg^-1) diets were prepared and fed to the fish three times daily to apparent satiation. Weight gain, feed conversion ratio (FCR), specific growth rate (SGR) and protein efficiency ratio (PER) were significantly affected by dietary choline (p<0.05). The best growth performance was observed in fish fed diets containing 2 and 8 g kg ^-1 choline (p<0.05). Fish fed with 2 and 4 g kg ^-1 choline showed higher lipid content compared with the control diet (p<0.05), but not significantly different in body protein (p>0.05). Total lipid of liver and plasma, plasma cholesterol, triglyceride and phospholipids levels showed an increasing trend with increasing levels of dietary choline, but not significantly different among treatments (p>0.05). Based on the results, we recommend adding a 1.5 gkg^-1 choline to commercial diet of juvenile Acipenser baerii.

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Death, existence and creation’s mystery are among of the most important subjects in literature and philosophy. Paul Valery and Khayyam, in spite of difference in their historical periods, have the same idea about death and existence. In his poem, Valery describes a marine vista, which is the symbol of boundless soul. However, in this sight, by passage of the time, the soul is worn-out and destroyed. Khayyam in his Rubaiyat considers fruitless thinking about the existence and the creation’s mystery. In this article, we try to survey the concept of death and existence in Paul Valery’s “The Graveyard by the Sea” and Khayyam’s Rubaiyat, Finally, these questions would be replied: “Why Paul Valery and Khayyam feared from death?” “Whether this fear arouses from their pessimistic and narrow minded view or it has existentialism fundamental?” and “How does the poetical imagination change to be a scene for speaking of the depth of poet’s philosophical vision about death?”

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Theme as the central thought and the main word of the artist is interpreted in the text and content. Theme is the main essence of literary work that illuminates the direction of thought and idea of its author. Couplet is one of the most pleasing Persian poetry forms with chiliad written history. Perhaps its oral history is even older. This form, along with the Persian traditional poetry, has grown in different languages of Iran. One of these languages, namely “Mazandarani” has a remarkable literature itself.In this article, the themes of two hundred folk couplets of Savadkouh (a city in Mazandaran) have been analyzed. The findings indicated that most of the themes are socially-oriented.the study analyzes seven themes in two-hundred couplets.the themes are: pain of love, sorrow of nostalgia, curse, complaints of young ladies for imposed marriages, as well as dissatisfaction with the fortune and luck, compulsory military service and the complaint of lover from beloved. Most of the couplets are monologues, which have been composed for the regret and reminiscence of the past days. Some of the important factors leading these couplets are analogy, rivalry, treason, financial poverty, illiteracy, hard work in strange lands, system of lord and vassal or mastery system, denial of other cultures, and cultural hybridity.

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SHAH BAJI lyric poem (MANZUMEH SHAH BAJI) is one of the most beautiful lyric poems of native literature of Mazandaran dated back to the late Qajar period and the first Pahlavi. The poem was composed by Mullah Khan Jan Heydari, a cattle rancher of LAFOUR (located on SHIRGAH, SAVADKOOH County). In terms of prosodic rhythmic structure, the poem can be read both in Hazaj or Mutaqarab meters. It depends on the narrators to decide to read the poem in any rhythm. Using formalist analysis, this study aims to find out how the components of formalism have been reflected in this lyric poem? The research results indicate that, among different kinds of deviations, the semantic deviation and its subtypes and time deviation have been more frequent than the others. Among different meters, lexical rhythm and its outstanding component namely Parallel Rhyming Prose (SAJ’ MOTEVAZI) are more seen in poem. The frequent repetition of long vowel /a:/ and the consonants like "r" , "l" , "m" and "n" in the poem, can be due to the more frequent use of these vowels and consonants in Mazandarani dialect to make rhymes.

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Imagology is one of the literary theories in comparative literature .Imagologie's component can be considered in six components: cliché, mold pattern, pre judgment, image, symbol and myth. In this article, foreign's image in Ferdosi's Shahname is epic work which is in defense of Iranian's national country and it is analysed in aspect of stereotypes processing. cliche (public belief) is a expression that is used by water Lip Man in America for stating public belief among one group or culture. The result of this research is that the reflect of foreign's image in Shahname in form of stereotype processing contain 13/58 percent from all of the four cases of foreigns personalities which are surveyed in this research. According to cliché's component, foreign personalities in Shahname can be divided to three categories: a) foreign's personalities who are linked by marriage with Iran. B) personalities who are going to impose a power or taking taxes ,attacked to Iran. C) using Iran's hero's power in foreign country. Among this one, the most relationship with foreign is done by establishing adultery link laundering .ferdosi has drawn the cause and result of these relations by others unpleasantly.  

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Khatun-e-Chaharshanbesoori (Last Wednesday’s Khatun) is a Guilani legend which has a place beyond a typical legend in the culture of the people of Guilan because, in a ceremonial night, it has devoted many customs to itself. Hence, this myth is repeated by them every year.
In this paper, through expressing the legend of Khatun-e-Chaharshanbesoori, its semiotics and mythology has been addressed. Then, the theories are expressed and studied based on the theory of Mircea Eliade, which is among some ceremonial sample called images of gods and mythology, and the present human being repeats them, the following question is addressed: Is this legend rooted in ancient beliefs of Guilan inhibitants? In the initial response, it can be said that many ancient beliefs, in accordance with the conditions of time, place and its progress in various fields, are outdated or, it can see the traces of the mythological themes in fairy tales and ritual.
Using the methodology of data collection in libraries and data analysis, the present article aims to examine the symbolic and mythical implications of Khatun- Chaharshanbesoori, and the rituals and beliefs relating to it in Guilan province.
 

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Regarding the importance of inhibiting VEGF and unique features of VHHs as a new generation of antibody-based therapeutics, the present study aimed to generate VHHs against the receptor binding domain of VEGF, thereby blocking of VEGF binding to its receptor. After preparing the gene repertoire of VHH fragments from an immunized camel, a VHH phage display library was constructed. We adopted a stringent successive biopanning to isolate the phages displaying VHH with high affinity to VEGF-RBD.A significant enrichment of phages that specifically bound to the target protein was obtained after six rounds of panning. Of the specific clones with high binding affinity screened by monoclonal phage ELISA, 52% shared the same VHH sequence, showing its high enrichment. Using molecular simulation of antigen-antibody interaction based on the crystallographic information of VEGF/VEGFR2, molecular dynamics simulations and MM/PBSA free energy calculations, we provide a reliable picture of the binding site of antibody on antigen. The key residues in the VEvhh1-VEGF interface were dissected and the energetics was analyzed by MM/PBSA. The results of studies revealed that VEvhh1 binds to the receptor binding site of VEGF with high binding energy and showed the highest affinity to the residues of VEGF which are responsible for VEGF binding to VEGFR2. Also the antibody potently covers these key functional residues of VEGF, thereby inhibiting VEGF binding to its receptor and probably abrogating its biological activity. This study may represent VEvhh1 as an anti-VEGF and anti-angiogenic candidate.

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Research subject: Iran is a country with high potentials for access to renewable energy sources such as solar, hydropower, wind, and biomass. Biodiesel is one of the renewable fuels that has always been proposed as a suitable and stable alternative (non-toxic, safe, and degradable) to fossil fuels.
Research approach: The experiences of different countries in the use of edible sources for biodiesel production shows that the use of edible sources has caused problems such as lack of food resources for human communities, lack of feed for livestock, and upsetting the balance in the food industry, and it can lead to a significant increase in the price of these resources. Therefore, many researchers have proposed the use of non-edible sources to address these problems. So far, very large non-edible sources for biodiesel production have been identified. In this paper, non-edible sources of biodiesel that are produced or have the potential to be produced in Iran are introduced and studied and a potential assessment study is presented for them.
Main results: In this work, the non-edible sources for biodiesel production are classified into four categories: agricultural waste, waste cooking oils, microalgae, and non-edible seeds. These sources are compared based on various parameters such as oil percentage, oil content per hectare, biodiesel production efficiency, viscosity, saponification number, and cultivation period, which according to the results, non-edible seeds, especially Nowruzak seeds, Castor, and safflower have been identified as the most rational and sustainable sources of biodiesel production in Iran. The present work also deals with the policies and incentives that the responsible institutions can apply for the prosperity of the biodiesel industry.

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The basis of Wittgenstein’s early thought is that concepts like God and values ​​have no representation in names, that is, they are never named, because names stand only for things that are simple, solid parts of the world. Since these things are never named and have no simple signs within the proposition to represent them in the proposition, no meaningful proposition can ever be formed about them and no meaningful talk can be said about them. If Wittgenstein’s theory had ended there, we would be right to call Wittgenstein a positivist. But the final paragraphs of the Tractatus provide evidence that a positivist interpretation of the Tractatus cannot be what Wittgenstein intended. Wittgenstein was not claiming that there is no God, that life is completely meaningless, and that values ​​are illusions; rather, his argument was directed at the limits of language. He said that one should remain silent about what is beyond the scope of language. 

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Aphis gossypii Glover is one of the major pests of cucumber in Iran. The effects of different concentrations of nitrogen (N1 = 0, N2 = 30, N3 = 60, N4 = 90 and N5 = 120 kg/ha), phosphorus (P1 = 0, P2 = 15 and P3 = 22.5 kg/ha) and silicon (Si1 = 0, Si2 = 100 and Si3 = 200 kg/ha) on life table parameters of apterous morph of A. gossypii were studied. This study was conducted as factorial experiment based on RCD with nine replications in a growth chamber at temperature of 25 ± 3 °C, 60 ± 5% relative humidity (RH) and a photoperiod of 16: 8 h (light: dark). The experiments were carried out using clip-cages that were fixed on leaves of cucumber growing in pots. According to the results, total fecundity of A. gossypii significantly was different among treatments and it was the highest on N1P2Si2 (64.33 offspring) and the lowest on N3P2Si1 (22.67 offspring). The lowest and the highest values of R0 were observed on N3P2Si1and N4P2Si2, respectively. The shortest mean generation time (T) was found on N4P1Si3 and the longest was on N5P3Si1. Furthermore, the lowest and the highest values of r were obtained on N5P3Si2 (0.27 day-1) and N5P1Si1 (0.41 day-1). Our results showed that in simultaneous application, the phosphorus had a more impact on life history and performance of cotton aphid.

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Aim: Breast cancer is the most common cancer in women.The Health Education Campaign (HEC) is an important educational strategy for breast cancer screening. The aim of this study was to investigate the effect of the (HEC) based training on the knowledge, attitudes, and practices of women, regarding breast cancer screening methods.
Materials & Methods: This was a pre- and post-quasi-experimental study conducted among 200 women over 20 years in Mazandaran Province. A self-made 34-item questionnaire was used to collect the data. A pretest was performed before the educational intervention and a posttest was conducted 12 weeks after the intervention. The data were analyzed by logistic regression, Pearson correlation coefficient, and one way ANOVA, using SPSS 22.
Findings: The mean age of the women was 35.16 years. Based on paired t-test, the difference in the mean scores of knowledge and attitudes regarding screening methods in the women was significant (p≤0.0001) before and after the intervention. Also, based on the macnemar test, the difference between the early detection of breast self-examination (BSE) and clinical breast examination (CBE) was significant in the women studied before and after the educational intervention.
Conclusion: According to the results of the study, the intervention had been able to change the knowledge, attitudes, and behaviors of women regarding breast cancer and early detection methods.
 

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This study was aimed to evaluate the effect of Levels of Choline on the growth performance (WG, SGR, FCR, CF, PER and HIS), Carcass Compositions, and Haematological of Caspian salmon. 270 (8.82±0.38 g) were randomly distributed in 18 fiber glass tank with treeplicatefor 10 weeks. Experimental diets were also prepared by adding 0, 250, 500, 750, 1000 and 2000 mg/kg the basal diet (Control, Cho250، Cho500, Cho1000 and Cho2000) to evaluategrowth performance, carcass composition, and some haematological parameters. The final weight, weight gain, specific growth rate index, proteinefficiency ratio, obesity coefficient, and feed conversion ratio of fish fed with diet containing appropriate levels of choline (750-1000 mg/kg^-1) were significantlyhigher than fish fed with other diets. With increasing choline in fish diet, body fatand protein concentrations significantly increased, but carcass moisture decreased. Also, addition of 750-1000 mg/kg^-1choline to diet caused a significant diference in the activity of liver enzymes (ALT, AST, ALP and LDH), compared with control treatment and 2000 mg/kg^-1.The results showed a significant increase in growth parameters and optimal carcasscomposition of Caspian salmon, the most suitable amount of choline is 750-1000 mg/kg^-1in the fish diet (p<0.05).
The results of this study indicated, that dietaryup to 1000 mg/kg^-1 to be negetivecooparation on growth performance, liver enzymesin Caspian salmon, salmo trutta caspius has moderate Choline requirement 750-1000 mg/kg^-1 as fed

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