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  Background: The innate immunity plays an important role in the host response to transplantation by Toll-like receptors and results in development of acute allograft rejection. The aim of this study was to evaluate the association of TLR2 and CD14 (co-receptor) gene polymorphisms with acute rejection in kidney transplant recipients.   Methods : The study was conducted in a population of 239 subjects consisting of 71 patients with acute rejection, 71 patients without acute rejection (SGF) and 97 Healthy Control (HC). The allele and genotype frequencies of TLR2 (R753Q, rs5743708) and CD14 (-159 C>T, rs2569190) polymorphisms were genotyped by Real-time PCR in the study groups. Results : Genotype distribution of CD14 -159 polymorphism was significantly different in AR vs. SGF and HC. CD14 -159 TT genotype was more prevalent in rejection than SGF and HC (P<0.0001, P<0.007, respectively). Also Graft loss, defiened as need of dialysis after acute rejection, was occurred in 24 patients (33.8%) from AR group. The frequencies of three genotype in CD14 (TT, CT, CC) in rejection With Graft loss were 75.0%, 20.8% and 4.1% respectively, While 25.5%, 31.9% and 42.5% in rejection without Graft loss (P<0.0001 for TT vs. CT, CC). Many recipients with AR were involved with graft loss had CD14 -159 TT genotype, whereas only a few recipients without graft loss had TT genotype (p<0.0001). Conclusion : Therefore, due to the importance of CD14 polymorphism (-159 C/T, rs2569190) in disease progression and also as a biomarker, could be considered as a crucial therapeutic target in early prognosis of acute rejection

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Objectives: In the last decade, public health planners have faced challenges related to the aging rate and the increase in mental health disorders. Research has shown that mental health issues are prevalent among older adults in Qazvin, but there hasn't been a comprehensive study on the impact of the social and built environment on mental health. Therefore, this research aims to identify the physical and social environment characteristics that can influence mental health.
Methods: This study is a cross-sectional quantitative research utilizing common mental health assessment tools, such as HADS and PSS, to gather data from 361 Qazvin's historical context residents. Additionally, an environmental quality questionnaire was used to collect information on the physical and social environment of the neighborhood. The collected data was analyzed using SPSS-25 software and the hierarchical regression method.
Results and Conclusion: The data analysis revealed that individual, place, and socio-cultural factors played a significant role in determining the mental health of older adults in Qazvin City. The individual factors that affected mental health included age, gender, home ownership status, and marital status. The place factors that influenced mental health included satisfaction with the place, land use, quality of residence, security, walkability, and access to green spaces. The socio-cultural dimension also played a role in mental health, as factors such as social support and cultural activities impacted the well-being of older adults. The results of this study can help in planning and designing neighborhoods in a historical context to improve mental health.              

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Aims: The psychological capital is one of the important indicators of positive psychology and it has positive outcomes for students. The present research aimed at studying the status of psychological capital of students in Kurdistan University of Medical Sciences and its related factors.
Instruments and Methods: The present descriptive-analytical cross sectional research was conducted among 384 students in Kurdistan University of Medical Sciences in 2016. The samples were selected by simple random sampling method.  Luthans et al.’s psychological capital questionnaire was employed for the data collection and data analysis was performed, using SPSS 22 software by descriptive statistics (mean and standard deviation) and inferential statistics (Mann-Whitney U test and Kruskal-Wallis test).
Findings: A total of 150 participants (39.2%) were male and 233 (60.8%) were female; 351 participants (91.6%) were single and 32 (8.4%) were married. The mean score of the psychological capital of students was 89.09±9.98. Minimum and maximum means were measured for Optimism and Self-efficacy. There was a significant relationship between sex, field of study, academic degree, and faculty place with psychological capital (p<0.05).
Conclusion: Factors such as sex, field of study, academic degree, and faculty place are effective in the psychological capital of students.

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Aims: This study was carried out to determine the prevalence rate of academic burnout and its related factors among the students of Kurdistan University of Medical Sciences in 2017.
Materials & Methods: The method of the present study was a descriptive survey method. The statistical community of this study included all students of Kurdistan University of Medical Sciences among whom 382 students. Maslach questionnaire of academic burnout (1999) was employed for data collection and data analysis was performed using SPSS 16 software, descriptive statistics (mean, standard deviation) and inferential statistics (Mann Whitney U, Kruskal-Wallis).
Findings: The average age of the students under study was 21.51±2.08. Two hundred and sixteen participants (56.5%) were male and 166 (43.5%) were female. 22 participants (5.8%) had associate's degrees, 315 participants (82.5%) were undergraduate and 45 participants (11.8%) were studying in Master and higher levels. 357 students (93.5%) were single and 25 (6.5%) were married. Mean score of the academic burnout of students who participated in the study was 60.88±9.98. The results of data analysis showed that there has been a significant relationship between gender and place of university in one hand and academic burn out in another hand (p≤0.01) as well as between major of study and academic burnout (p≤0.05).
Conclusion: A significant percentage of students are suffering from academic burnout. Also, students with different majors of study may experience a different academic burnouts.
 

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Sardari is one of the most important landraces of common wheat (Triticum aestivum L.) that is mainly cultivated in drylands and mountainous area of Iran. Moreover, it shows a high level of genetic diversity. In the present research a total of 73 Sardari wheat ecotypes were evaluated for drought tolerance. Genetic diversity was analyzed using amplified fragment length polymorphism (AFLP) marker based on three pairs of primer combinations. Of the 2,431 AFLP bands detected, 1,582 (73.92%) were polymorphic. Cluster analysis divided all ecotypes into eight major groups. Ecotypes also showed genetic diversity for drought tolerance and were classified into three groups. The first group consisted of forty-two of the 73 landraces and had a low stress tolerance index (STI), ranging from 0.165 to 0.401, while the second (23 landraces) and the third group (7 landraces) had a medium and high STI ranging from 0.425 to 0.640 and 0.662 to 0.817, respectively. Discriminant analysis (DA) identified twenty-four markers selected from 218 AFLP markers that accounted for the difference between the three phenotypic groups. By using the selected markers, DA validated the phenotypic grouping, with a zero error rate. The results showed a high degree of genetic diversity between the Sardari ecotypes, suggesting that Sardari can be used as a germplasm source for wheat improvement toward releasing more desirable cultivars.

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The purpose of the present study is to investigate the sub-worlds in Werth's Text Worlds Theory (1999) based on Cognitive Poetics Approach. Upon analysis, the authors showed that up to what extent the writer of Blind owl has used the sub-worlds including deictic, attitudinal, and epistemic. The methodological nature of this qualitative research is descriptive-analytic. It should be noted that all the clauses have been examined. But due to the limitation of the paper volume, in only 20 clauses of this story, the three sub-worlds have been analyzed as one of the semantic layers in Werth's Text Worlds Theory. The authors sought to illustrate the representation of the three sub-worlds in Blind owl and the way the writer has used these three layers in the story. The findings indicated that the epistemic sub-world has been used significantly more than other two sub-worlds, i.e. deictic and attitudinal. Also, the results showed that most of the clauses are narrative and discursive, and the epistemic sub-world has been reflected widely in this story.
Extended Abstract
The Aim of Research: The purpose of the present study is to investigate the sub-worlds in Werth's Text Worlds Theory (1999) based on Cognitive Poetics Approach. With this investigation, the authors showed that up to what extent the writer of Blind owl has used the sub-worlds including deictic, attitudinal, and epistemic. The present study seeks to show that any text based on Text Worlds Theory in the cognitive poetics approach can be examined in the form of three layers of text world, discourse world and sub-worlds which the authors have tried to explore the three layers of the semantic layer of sub-worlds including, deictic, attitudinal, and epistemic in the story of Blind owl. In this regard, we try to use the theory of cognitive poetics to achieve a correct reading of these texts that is far from any personal interpretations. It is worth noting that showing different semantic layers and understanding them correctly is possible only by applying this theory.
Methodology: The methodological nature of this qualitative research has been descriptive-analytical. The authors collected data by reading and analyzing the text of the story of “Blind Owl” by Sadegh Hedayat. In reviewing the clauses of this story, due to the limited volume of the article, the authors considered 20 clauses of the story from the perspective of the three layers of the sub-worlds as one of the semantic layers in the theory of text worlds in the cognitive approach from the perspective of Werth (1999).
Theoretical Framework: The theoretical framework of this research is informed by the approach of cognitive poetics in linguistics and Werth’s Text World Theory (1999). What makes this theory unique is its comprehensive application of cognitive principles in analysis. Text worlds Theory is a discourse framework, in the sense that its attention is not only focused on a particular text, but also on the contextual context and its surroundings that influence its production and acceptance. The purpose of this theory is to provide a framework for studying discourse in which situational, social, historical and psychological factors are involved and play an important role in language cognition (Gavins, 2007). Werth’s book was published after his death by Short in 1999 titled Text Worlds: Representation of Conceptual Space in Discourse, that includes Werth's full account of this theory. According to Johnson (1987), the cognitive approach shows that language is a product that is not produced from a separate structural system in the mind, but from cognitive processes that enable the human mind to make perceptions of experiences which linguists call them embodied cognition (Freeman, 2000, p. 281). Also, Stockwel (2002) states a broader concept of cognitive poetics and introduces all approaches that provide a framework for describing literary texts based on the tools of cognitive science, with the label of cognitive poetics. Text worlds are mental structures that form conceptual representations of certain aspects of reality. Werth's model is based on the distinction between two prominent functions of language: the informative function and modal function. Werth considers the informative function as what is often called the propositional meaning.
Conclusion: In this study, we have examined and evaluated the story of Blind Owl, by Sadegh Hedayat, based on the theory of ​​Text Worlds in the cognitive poetics approach, and it has been determined how the writer of the story has acted in order to understand the reader. It is worth noting that the three sub-worlds of deictic, attitudinal and epistemic, represent an important part of the construction and formation of the worlds of the story text. In order to fully understand the text, one must describe and analyze a part of it in order to determine the idea of ​​the text through the text itself, and not through utterances that are formed outside the text. The theory of ​​text worlds based on the approach of cognitive poetics opens a new path in literary criticism, the discovery of how the mind works, the relationships between time, and anything else that helps to build the reader's mental representation. Hence, this approach is a bridge between literary studies and the field of cognitive linguistics. To answer the first question, it should be said that Sadegh Hedayat has used more narrative and discursive text in this story. Regarding the second question, it must be acknowledged that although the three sub-worlds of deictic, attitudinal and epistemic are observed in the Blind Owl, but the sub-world of epistemic plays a decisive role through conditional sentences, frequency adverbs, cognitive metaphors and repetition. The findings indicated that three sub-worlds including 29.63% deictic, 33.33% attitudinal and 37.04% epistemic, have been used in the story of Blind Owl. The results also showed that the epistemic sub-world has the highest usage and the deictic sub-world has the lowest usage in this story.
 

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The Effect of different levels of Wood Betony (WB), Stachys lavandulifolia extract, as complement in feed, on the performance of common carp, Cyprinus carpio was evaluated. The fish (44±0.62 g) was assigned to four treatments, three replicates each. The fish was fed on normal diet with no WB (control) vs. diet containing 2, 4 and 8% of WB extract. Fish were successively fed on the diet, 2% live body weight, three daily for 70 days. The results revealed that final weight, mean weight gain and specific growth rate were significantly improved by increasing WBlevels in the diet. The highest growth performance and the lowest feed conversion ratio were recorded for 8%WBtreatment. No significant changes were observed in the proximate whole body composition among different groups. Hemoglobin content and hematocrit value increased significantly in the second group in comparison with the others (P< 0.05). The highest serum total protein (5.05±1.4 g dl^-1) and globulin (2.47±0.3 g dl^-1) were recorded in the fish fed on the highest dose of WB (8%). Inclusion of 2% of WB in the diet reduced serum triglycerides (317.44±89 mg dl^-1) and cholesterol (141.51±35 mg dl^-1) in comparison with control (P< 0.05). It could be concluded that feeding common carp with the diet enriched with WB extract could enhance growth rate, improve some hematological and biochemical characteristics with no adverse effects on body composition. 

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In present work, heat transfer and flow pattern map of dimpled and horizontal tubes were studied during phases of boiling and condensation of mandatory convection of hydrocarbon R600-a. Empirical relationship will be expressed based on empirical data obtained by such experiments and fit the experimental results and Matlab software to show flow pattern map for such refrigerant with proper accuracy. The cycle consists of a pump, two preheaters, two testing parts, two condensers, flow meter and reversing valve. In this study, experimental evaporator is a copper tube with internal diameter of 8.7 mm and length of 1200 mm. the heat required for fluid evaporation is supplied by thermal element twisted around it. Such tube has been designed in forms of dimpled and straight models to evaluate effect of placement of dimples inside tubes. The test was conducted by refrigerant mass flow between 155 and 470 kg/m^2 s and vapor quality between 0.05 and 0.78. Moreover, flow patterns and their transitions for refrigerant R-600a during flow boiling inside a helically dimpled tube and a smooth tube were visually observed and analyzed. Annular, intermittent, and stratified-wavy flow were recognized for plain tube whereas there was no stratified-wavy flow in flow pattern visualization of dimpled tube. Investigation clearly shows that the dimples in evaporation significantly impact the two phase flow pattern. Inside the helically dimpled tube the intermittent/annular transitions occurs at lower vapor quality value than for the smooth tube.

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This paper presents an experimental and numerical investigation of phase change material melting in a rectangular enclosure. The aim of this research is the study of the effect of the tilt angle of the enclosure on the flow structures and the melting rate. In the experimental section, the visualization of the melting process is carried out by the photography of the phase change material through a transparent enclosure. Then, the image processing of the photographs is performed to calculate the instantaneous liquid fractions. The variation of the solid-liquid interface by tilting the enclosure clearly implies the evolution of the flow structures in the liquid phase. Numerical simulation is performed using the enthalpy-porosity approach for tilt angles of 90, 45 and 0o and wall temperatures of 55, 60 and 70 oC. The results show that by decreasing the tilt angle from 90o to 45o and 0o, the melting times are 52% and 37% less than that of the vertical enclosure. Melting time reduction in the inclined enclosure is due to the formation of the vertical flow structures and thermal plums in the liquid phase. By Increasing the Stefan number from 0.36 to 0.43 and 0.55 the thermal energy storage increase by 5.4% and 13.8%, respectively. Also, a correlation is developed to predict the thermal energy storage in the tilt enclosures using nonlinear regression.

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This paper discussed nonlinear adaptive control of a 6 DOF biped robot. The studied robot was divided to three part, fix leg, moving leg and a torso and all the joints were considered rotational. Generally, for calculations, robots are considered as a whole which makes the related calculations complex. For balance calculations, the zero moment point (ZMP) was either considered as a fix point on the ground or a moving point on the foot plate. In the presented robot in this study with priority of movements, first, the calculations were carried out on the moving foot, then the effect of the motion on the foot was inspected and a pendulum was used to balance the robot. To check the balance, ZMP in the simulation in MATLAB software was considered as a fix point While in Adams software simulation, ZMP was considered moving along the bottom of the sole. All the charts active with both software met each other. In the presented study the inverse kinematics was calculated by trigonometric method and inverse dynamics of each leg was investigated by Newton-Euler iterative method. All calculations were carried out in MATLAB software and were verified by ADAMS software. By writing the equilibrium equations, the angle of torso at each time was achieved. In the next step, because of uncertainties in manufacturing and some parameters like mass, length, etc. adaptive computed torque control was used on each leg to achieve the maximum torque that each joint needs for stable walking.

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The ­antifeedant activity of nanoemulsion formulation of arugula Eruca sativa Mill. oil was studied against elm leaf beetle Xanthogaleruca luteola (Müller)(Col.:Chrysomelidae) under laboratory conditions at 25±1ºC, 75±5% RH, and LD 16:8 hours. Ingestive LC₅₀ values of the oil were studied in third instar larvae. Then, physiological parameters were evaluated following 24, 48, and 72 hours post feeding at LC₅₀ level. LC₅₀ values 24, 48 and 72 hours after application were 4.940, 3.791, and 2.938 mg mL^-1, respectively. Arugula oil at LC₅₀ level decreased the nutritional indices including efficiency of conversion of ingested food, relative growth rate, efficiency of conversion of digested food, and relative consumption rate, but increased feeding deterrence index significantly 72 hours post feeding. Nutritional reserves such as total carbohydrate, protein, and lipid contents and also digestive enzymes containing lipase, α-amylase, and protease activity were decreased showing post-ingestive toxicity. The activity of the detoxifying enzyme glutathione S-transferase was increased, indicating that this enzyme may be involved in detoxification of arugula oil, but general esterase did not change significantly. In general, it can be concluded that arugula oil possess antifeedant activity against X. luteola under laboratory condition. It seems that arugula oil has a great potential to be used as effective botanical pesticides. However, further studies such as greenhouse and field experiments are necessary before recommendation and commercialization process.