Showing 89 results for Dehghani
Volume 8, Issue 4 (3-2019)
Abstract
Today, developed and developing countries are focusing more on environmental issues and development. The present study aims to provide a model for the establishment of green human resources management in the entrepreneurship ecosystem. The purpose of this research is in the field of applied research, and since it describes the variables and relationships between them, the recognition of the status quo and finally the presentation of the pattern of deployment, is descriptive-survey method. The statistical population of this research includes relevant experts. In order to reach the consensus, 27 people were studied by interview method and the required information was collected. To analyze qualitative data and to extract factors affecting HRM and its influential factors, the method of analysis of the theme (theme analysis) was used. Structural-interpretive modeling has been used to identify the relationships between variables and the deployment of green human resources in the entrepreneurship ecosystem. The findings of the research include explaining the green human resources management model in the entrepreneurship ecosystem and analyzing the results of infiltration-correlation; the existing model is a model for different businesses with the aim of establishing a green human resource management in the entrepreneurship ecosystem. The research findings show 18 dimensions for the establishment of green human resources management. The research results indicate the impact of green human resource management on entrepreneurship ecosystems and green thinking and sustainable development, and ultimately globalization.
Volume 8, Issue 15 (Spring & Summer 2021)
Abstract
One of the means of translating the Quran is to pay attention to the origin of the meaning of the words of the verses, which paves the way for explaining the meaning of the text. To understand the main words in the verses, the principle of basic meaning, etymology and its meaning in different contexts should be considered. One of the most frequent words in the Holy Quran is the words taken from the article "Nafaq" in a way that for finding an equivalence, the two words "charity" and "hypocrite" are always considered independent due to semantic distance and positive and negative emotional connotation because of not paying attention to the derivation from the principle of matter, and they show the meanings away from the basic meaning. The present research seeks to answer the questions in a descriptive-analytical method, what semantic course has the article "Nafaq" gone through and what components has it in this course? And what is the semantic relationship between the derivatives of this article? The findings of the research indicate that in pre-Islamic Arabic texts and their common scientific language, the word "Nafaq" was used in the meaning of "hole". The Holy Quran created a special culture for the meaning of this word and based on meanings of the hole and the rift, the three words "hypocrite", "charity" and "alimony" has been conceptualized from the article "Nafaq". The difference is that in Quran and in the light of the prototype view, the meanings of "Nafaq" are more limited and it is used in the two areas of charity and spending wealth, as well as hypocrisy and duplicity in beliefs. Based on the original prototype in the scientific language, these meanings have been illustrated and conceptualized in a way that it is necessary for the translators to pay attention to these conceptualizations in the translation of the Quran.
Volume 9, Issue 2 (Spring 2020)
Abstract
The aim of the present study was to identify the phytoplankton species which producing domoic acid and okadaic acid toxins in coastal waters of Banar Abbas city, and to determine the concentration of domoic acid and okadaic acid toxins in water and shellfish samples.Water sampling was performed in winter 2015 and summer 2016 from coastal areas overlooking the discharge of municipal and industrial effluents. Shellfish were collected from the coasts of Bandar Abbas and Bandar-e- Lengeh. Phytoplankton toxins were measured by kit method and instrumental analysis based on ELIZA method.Pseudonitzschia delicatissima, Pseudo-nitzschia pungens and Pseudo-nitzschia seriata were identified in the production of domoic acid, while Dinophysis caudate and Prorocentrum Lima were recorded as okadaic acid producers in the coastal waters of Bandar Abbas. Water-soluble okadaic acid showed significantly higher concentrations than domoic acid. Instudied shellfish samples (Circenita callipyga, Barbatia candida, Telescopium telescopiumandThalessa savignyi), the measured concentrations of okadaic acid ranged from 59.8 ± 2.38 to 121.96 ± 28.25 μg / kg. This value for domoic acid was from 0.85 to 83.59 ± 38.72 μg / kg.Compared to the guideline values, the observed concentrations of okadaic acid and domoic acid toxins in the studied shellfish were lower than the allowable level. But this value was recorded for the water-soluble domoic acid above the allowable value, which requires continuous monitoring to achieve the quantitative and qualitative pattern of phytoplankton toxins in order to support the safety of the marine ecosystem users in Hormozgan province.
Volume 9, Issue 2 (Spring 2024)
Abstract
Aims: The primary objective of this study is to examine the relationship between alexithymia and Post-Traumatic Stress Disorder (PTSD) among patients experiencing varying degrees of Chronic Pain (CP).
Method and Materials: This study utilized a descriptive causal-comparative approach. The participants were drawn from patients referred to pain and physiotherapy clinics in Tehran from 2022 to 2023. Out of 300 CP patients, 150 patients with high CP levels and an equal number with low CP levels were purposively chosen. The participants completed the Graded Chronic Pain Scale (GCPS), Perth Alexithymia Questionnaire (PAQ), and Post- traumatic Stress Disorder Checklist (PCL). Data analysis was performed using SPSS-24 software, employing multivariate analysis of variance.
Findings: The findings revealed a significant difference in the levels of alexithymia and PTSD between the two groups (P<0.001). Patients with high levels of CP demonstrated increased negative-difficulty identifying feelings (F=241.87), positive-difficulty identifying feelings (F=389.01), negative-difficulty describing feelings (F=190.61), positive-difficulty describing feelings (F=347.81), general-externally orientated thinking (F=376.28), re- experiencing (F=246.75), avoidance (F=100.74), negative alterations (F=378.01), hyper-arousal (F=388.46), and emotional numbness (F=388.47) compared to their counterparts(P<0.001).
Conclusion: These findings underscore the intricate relationship between CP, alexithymia, and PTSD. Therefore, the need for comprehensive assessment and management strategies addressing the interplay of these factors in patient care is highlighted.
Volume 9, Issue 3 (Summer 2021)
Abstract
Aims: The global need for water-conserving increasing in arid and semi-arid areas and water preserving by improving vegetative cover in rangelands by reducing the erosion effects is a rational justification for the performance of underground dams. This research aimed to locate underground dams using GIS integrated with the fuzzy algorithm.
Materials & Methods: The data layers included geology, LU/LC, streams, villages, water resources, and slopes of the Sarakhs region, Iran, were prepared and standardized by the sigmoidal membership function.
Findings: Almost 98% of the final maps were in the fuzzy range of 0 to 0.5. This means that suitable locations for constructing underground dams with the fuzzy range of 0.5 to 1 found in less than 2% of the Sarakhs basin.
Conclusion: The superiority of fuzzy method for more scalability from other overlaying methods comes from this fact that in the second step of site selection and in the different management scenarios, we can take advantage from multiple fuzzy ranges.
Volume 10, Issue 1 (6-2010)
Abstract
Abstract
Due to various deficiencies, inadequate lateral stiffness, weak design and weak construction, many reinforced
concrete buildings are highly damaged during the major earthquakes. One way to retrofit these buildings is to
improve the behavior and to prevent the total collapse of the reinforce masonry infilled walls in order to make
them behave such as structural walls with composite materials.
In this study, the concept of equivalent strut is investigated by finite element modeling and behavior of the
compression strut and tension tie is presented to model unretrofit and retrofit masonry infilled walls. Analytical
pushover results show great accordance with experimental results.
Volume 10, Issue 1 (10-2021)
Abstract
Gut bacterial symbionts have an essential role in the nutrition and fitness of xylophagous insects. These bacteria produce several enzymes like cellulase and laccase which are important in industrial applications. In this study, laccase-producing bacteria were isolated and identified from the gut of the wood borer leopard moth. Four novel laccase positive strains were isolated using guaiacol-containing agar plates. Among the strains of dc4f, le2f, lc2, and lb8, the strain le2f displayed high laccase activity of 0.059 U ml-1 toward syringaldazine as a typical laccase substrate. The isolates were identified based on biochemical tests and 16S rRNA gene sequencing analyses. Nucleotide BLAST analyses of 16S rRNA gene sequence exhibited that the strains of dc4f, lb8, lc2, and le2f, had the most similarity (with more than 98% identity) with Enterobacter sp. strain W-6 16S (ACCN: MK505390), Serratia liquefaciens strain N112 (ACCN: MK629784), Brevibacterium sp. strain 773 (ACCN: MH777897) and Staphylococcus sciuri strain KSI 708 (ACCN: KC113150), respectively. Overall, the current study is the first research on alkaliphilic bacterial strains from the gut of leopard moth with laccase activity.
Volume 10, Issue 2 (Number 2 - 2008)
Abstract
In order to increase grain yield, nitrogen use efficiency (NUE) and nitrogen apparent recovery fraction (NARF) in wheat (Triticum aestivum L.), this experiment was carried out with 5 or 6 treatments and 3 or 4 replications in 14 locations at 22 different sites in Iran during the 2004-05 growing season. The experiment was designed as a completely randomized block. The effect of N sources and timing on the grain yield, protein content, NUE and NARF of the current best adapted cultivars of different regions were evaluated. The treatments included T1= the control; T2= 150 kg ha-1 of N as urea in 3-split applica-tions; T3= 150 kg ha-1 of N as urea in 2-split applications; T4= 150 kg ha-1 N as SCU as the base fertilizer; T5= 1/3 N as SCU as the base fertilizer +2-split urea applications and T6=1/3 N as complete fertilizer as the base fertilizer +2-split urea applications. Protein content, NUE and NARF were calculated by measuring grain yield, N% and N-uptake. While the average grain yield and protein% for the control plots were 2,840 kg ha-1 and 10.03%; the yield and protein for T2, T3 and T4 were 4,160 kg ha-1 and 11.66%; 4,278 kg ha-1 and 11.78%; and 3,921 kg ha-1 and 11.60%, respectively. Grain yield and protein content for T5 were 4,330 kg kg-1 and 11.89%. Yield of 4,674 kg ha-1 and protein content of 12.01% were ob-tained by substituting complete fertilizer with 1/3 urea (T6). The grain yield for T6 was significantly different from T2 for various reasons, including higher levels of available P, K, S, Zn, lower N-leaching and appropriate N-timing. NUE for T2, T3, T4, T5, and T6 was measured to be 8.8, 9.6, 7.3, 9.9, and 12.2 kg kg-1, respectively, and NARF were calculated to be 23.2, 25.3, 19.4, 26.3 and 31.6%, respectively. While the superiority of complete and SCU fertilizers over pre-plant urea has been proven, especially in the light-textured soils, it is highly recommended that the experiment be further tested and evaluated, since this practice has been increased the grain yield up to 12%, NUE up to 39 kg kg-1 and NARF up to 36% in comparison with the best wheat growers’ N-fertilization practice.
Volume 10, Issue 4 (Issue 4 (Tome 49)- 2007)
Abstract
Empirical sciences are systems of theories. Scientifics theories build up the human’s knowledge realm through explaining the phenomena and develop it by raising new issues and participating in the formation of new theories in responding them .
This article presents a systematic method for theory building in managerial Studies as well as human oriented researches. The theories take shape by means of extracting and organizing the “concepts” hidden in the research subjects. This logic merges the empirical knowledge (singular statement)with the theorems (universal statements) by justification and generates new deductive theorems with scientific validity. Thus, in the present research “Grounded Theory”(GT) was presented as a widely accepted methodology and the theory building process was explained by means of GT.
An experience of theory building in managerial research was then presented to enlighten the process more clearly. This research studied twelve failed companies to find out the reasons behind the crashed strategies and the findings were presented in the pattern of two theories. The trustworthiness of the two theories was introduced through "falsification" at the end of the article.
The main purpose of this research was to familiarize the human science researchers with “theory building” and to report an actual work through the use of this me methodology. Even though it was restricted to summarizing due to its short structure.
Volume 10, Issue 4 (Fall 2024)
Abstract
Background: Viral infections may play a significant role in the development of heart failure, especially in people with related cardiac conditions such as myocarditis. Hepatitis B and D viruses (HBV-HDV) are potentially fatal liver infections. This study examined the influence of metabolic syndrome and its associated disorders.
Materials & Methods: This cross-sectional study investigated hepatitis D antibody and hepatitis B surface antigen (HBsAg) in 239 people aged 35 to 65 years in Mashhad, Khorasan Razavi Province, Iran in 2018-2019. There were two study groups: those with cardiovascular diseases (CVD) and healthy individuals. Serum samples of all subjects in both groups were examined using enzyme-linked immunosorbent assay (ELISA).
Findings: HDV infection was detected in none of the study groups. Only one patient (0.8%) in the case group tested positive for HBsAg. The average LDL (low-density lipoprotein) (p= .8) and cholesterol (p= .3) levels in terms of lipid profiles were similar in both groups. Although the mean high-density lipoprotein (HDL) level in the patient group was lower, the mean triglyceride level in this group was higher than in the control group. Fasting blood sugar (FBS) (p= .009) and aspartate aminotransferase (AST) levels were significantly higher in CVD patients, while 59.3% of them exhibited metabolic syndrome.
Conclusion: This study results demonstrate no connection between HBV/HDV infection and cardiovascular diseases. The findings confirm that metabolic syndrome and hyperglycemia are underlying factors in cardiovascular diseases. Changes in HDL and triglyceride levels could impact cardiovascular diseases more than other lipids.
Volume 11, Issue 1 (Winter 2023)
Abstract
Aims: Despite the benefits of Patient-Centered Communication (PCC), there are problems with its implementation. Problems are related to characteristics of patients or health systems, patterns of patient-physician interaction, or perspectives in defining PCC. This study aimed to examine determinants of PCC from the viewpoint of faculty members, medical residents and interns, and patients and recommends tips for improving Patient-Physician Relationships (PPR).
Participants & Methods: In this qualitative content analysis study in 2018 at Tabriz University of Medical Sciences, data were gathered using focus groups (62 participants), semi-structured interviews (31 participants), and participatory observations based on purposive until the saturation was achieved. The content was analyzed through a thematic, manifest summative analysis. Standards for methodological rigor were enhanced through different strategies.
Findings: The findings were classified into four categories matched with four core concepts of PCC: 1) Respect and dignity, 2) Information sharing, 3) Participation, and 4) Collaboration. Sub-categories included recognition of patients’ individuality, attention to patients’ needs, physicians’ personal characteristics, physicians’ communication competencies, patient-focused care, patients’ trust-supported attitude, physicians’ motivation, physicians’ working context, socio-cultural inductions, organizational policies, and physicians’ professional responsibility.
Conclusion: Patient-centered communication can be characterized by honoring patients’ individuality, paying attention to patients’ needs, focusing on physicians’ proper personal characteristics in continuing medical education, enhancing physicians’ communication competencies, institutionalization of patient-focused care, creating trust-supported attitudes among patients, increasing physicians’ motivation, regulating physicians’ working context, serious attention to social and cultural inductions, making supportive organizational policies, and evaluating physicians’ professional responsibilities.
Volume 11, Issue 2 (3-2020)
Abstract
surveying the content of Fars local periodical literatures at the late of Qajar and the beginning of Pahlavi shows that women had an effective role in the political and social activities like as the anti-authoritarian and constitutionalist movement and they had could raise their level of political and social awareness. Women in the form of communities and associations and using the magazines which were the most prevailing device at that time, tried to implement the changes in full for the society. Such efforts resulted in political and social awareness of Fars women and the whispering of the issue of women's social rights. Fars province women, through numerous articles of magazines, and for the first time acquainted with the women rights such as the right to education, the right to trade, etc. and gradually they sought to earn the aforementioned rights in the realm of action. The article is concerned on the extension of press and its influence on the process of political-social awareness and women's identity formation to assert their basic rights. The findings of the study show that the Fars press at this era was essentially self-disciplinary with the continuous pursuit of social and political rights for women and greatly assisted women to identify their rights and being socialized. The research method, since the main sources of research in the press, is based on textual analysis, which can be considered as a deeper level of descriptive-analytical method that ultimately leads to appropriate explanations.
Volume 11, Issue 3 (Number 3 - 2009)
Abstract
Investigation of the interrelationships between yield and its components will improve the efficiency of a breeding program with appropriate selection criteria. In this study, the relationship among yield components and their direct and indirect influences on the total yield of melon were investigated. The study was based on evaluation of 49 entries gener-ated from a 7×7 diallel involving Iranian melon landraces under two conditions of cultiva-tion, pruning and non-pruning. A sequential path model was used for ordering the vari-ous variables in first and second-order paths based on their maximum direct effect and minimal colinearity. Two first-order variables, namely the number of fruits per plant and average weight of fruits per plant accounted for 91% and 83% of total variation in total weight per plant under the pruning and non-pruning conditions, respectively. The direct effects of these two variables on total weight per plant under non-pruning conditions were nearly equal, but the direct effect of average weight of fruits per plant in the pruning data set was much higher than the number of fruits per plant (1.14 vs. 0.73). All direct effects were found to be significant as indicated by bootstrap analysis. The results indicated the utility of the sequential path model for determining the interrelationships between yield and related traits in melon.
Volume 11, Issue 3 (11-2011)
Abstract
Abstract :Side sluice gates are flow metering structures, which are used for controlling the flow from the main
channel to the side channel. It is usually required to determine the discharge coefficient for estimation
of the side sluice gate discharge. In order to study the influence of some important parameters on the
discharge coefficient of side sluice gate, extensive experiments were conducted. The experiments were
conducted in a re-circulating channel having a central angle of 180o, a centerline radius of RC = 2.6 m,
and the width and height of 0.6 m. The ratio of radius of centerline of the channel to the width of the
channel Rc/B was 4.33. The bend was connected to two straight upstream and downstream reaches.
The upstream one was 7.2 m in length while the length of downstream one was 5.2 m. The bed and
sides of the channel were made of glass and supported with metal frames. The side channel was set at
different locations of bend (i.e. at the sections 53, 65, 90, 115 and 135 degree). The side sluice gate
was made of Plexiglas and was set at the entrance of the side channel. The experiments were carried
out for different gate openings, upstream depth of flow and location of the side sluice gate under free
flow condition. The upstream discharge was measured by a digital flow meter, while the downstream
discharge was measured using a calibrated triangular weir. The difference of upstream discharge and
downstream discharge resulted to the sluice gate discharge.
The results of experiments on a side sluice gate located in a 180 degree curved channel are reported.
The variation of flow depth along the side sluice gate was studied. The influence of different
parameters like: depth of flow, approach Froude number, side sluice gate opening and location of side
sluice gate on discharge coefficient were investigated.
It was found that increase of approach Froude number increases the discharge coefficient. Moreover,
increase of relative flow depth h1/a increases the discharge coefficient. Here, h1 is the approach Froude
number and a is the sluice gate opening. Maximum discharge coefficient was observed when the
sluice gate was located at the section 150 degree in the channel bend.
New equation for discharge coefficient of a side sluice gate in a 180 degree curved channel was
developed. The discharge coefficient was found to be related to approach Froude number, location of
sluice gate in the channel bend and the relative flow depth
Volume 11, Issue 3 (8-2022)
Abstract
Estimation of coral fishes biomass is needed as a basic benchmark for assessing the ecological status and fishing potential of coral reefs. Different methods are used to sampling the biomass of these communities, that direct observation is one of the preferred methods with respect to the non-destructive advantage. The purpose of investigation was to estimation standing biomass of coral fishes by Underwater Visual Census method (UVCm) in Abu-Musa Island seasonally from October 2019 to September 2020. also confidence interval was calculated of these estimations from the bootstrapping test (95%). Standing biomass of Coral fish and their confidence interval (95%) by bootstrapping simulation (n=479) were determinated 2923.6 kg., 4576.2 kg, and 1645.4 kg for the stations one, two and three respectively. The difference in the biomass standing of coral fish in three station could be related to the lack of differences in the amount of developed reefs, coral communities and significant differences in habitat availability. Also, the standing biomass of coral fishes in the Abu-Musa Island are limited, that can be attributed to their low habitat, shortage of carrying capacity and the short life of the Persian Gulf basin, and stress that occurs in the ecosystem, especially bleaching events, that need more study in the future.
Volume 11, Issue 4 (Fall 2023)
Abstract
Aims: This study compared two groups of twin pregnancies complicated by twin-to-twin transfusion syndrome (TTTS), with and without selective fetal growth restriction (sFGR), and evaluated the survival rate at 30 days after birth treated with fetoscopic laser photocoagulation (FLP).
Materials & Methods: The present study was a retrospective study of 164 diamniotic monochorionic twin pregnancies complicated with TTTS and treated with FLP. The sFGR was defined as an estimated fetal weight below the 10th percentile. The independent t-test, Chi-square test, or Fisher's exact test were used for statistical analysis. Multiple logistic regression analysis was performed to identify 30-day donor twin survival risk factors for the entire study population. The significance level was determined at p<0.05.
Findings: Of the studied cases, 45.1% had only TTTS, while 54.9% had both TTTS and sFGR. .There was a significant difference (p<0.001) in the distribution of Quintero stages and maternal age during the intervention (p=0.01) between the two groups. The sFGR before laser surgery in TTTS patients was associated with reduced donor survival. The multivariate analysis revealed that gestational age at delivery (OR=0.81, 95%CI:0.7-0.8) and sFGR (OR=0.43, 95%CI:0.2-0.8) were significantly associated with donor survival.
Conclusion: The sFGR before FLP is present in approximately 55% of TTTS cases, which is caused by normal placental abnormalities. TTTS with sFGR is associated with reduced donor embryo survival. Gestational age at delivery and sFGR are important factors affecting donor survival 30 days after birth. Performing successive ultrasounds after diagnosing monochorionic twin pregnancies is essential for timely identification, correct management, and treatment.
Volume 12, Issue 3 (9-2023)
Abstract
The present study was conducted in order to obtain the necessary information on the diversity, abundance and distribution of macroinvertebrates, as well as to investigate the grazing status of batoid fishes (stingrays) from benthic macroinvertebrtes in coastal waters of Hormozgan province. For this purpose, sampling was done in the years 2017 and 2018 and once every year in the autumn season. At the end of the identification process, a number of 125 genus and 104 species belonging to 85 families, 31 classes, 9 orders, and 7 phyla were successfully identified. Results revealed that Malacostraca was the frequent order in the studied area. In order to investigate the possible relationship between composition and abundance of benthic macroinvertebrte and stingrays, CCA analysis was employed. Results of stomach content of stingrays revealed that in the diet of M. randall, crustacean (93.25 %IRI) has the highest amount. This pattern was the same for M. gerrardi and H. walga. However, in M. gerrardi, bivalvia were in the first place of importance (31.33 %IRI). Also, trophic level analysis was done for three species which shows all species are Mesopredators that place in the same level of food web. According to the mentioned cases, some benthic macroinvertebrates identified in this research have a significant relationship with the benthic fishes, which requires more studies to investigate their relationship.
Volume 12, Issue 58 (September -October 2024)
Abstract
The purpose of this study is to investigate the conceptual metaphors of anger in Dashti dialect. The theoretical foundations of this study are based on the approach proposed by Lakoff and Johnson (1980) about the conceptual structure of metaphors and Kovecse's (2005) regarding the role of cultural patterns in metaphorical conceptualization. This study uses the method suggested by Stefanovich (2006) under the title of metaphorical pattern analysis. For this purpose, language expressions that convey the concept of anger were provided and analyzed through interviews with 45 speakers (40 years old and older) of Dashti region and also by observing the linguistic behaviors of the speakers of this region. The data of this study, in addition to showing common and universal source domains, clearly reveal the influence of factors that arise from the climatic and cultural experiences of the speakers of this region.
Volume 13, Issue 1 (4-2013)
Abstract
Central nervous system (CNS) uses an abundant set of joints and muscles to ensure both flexible and stable movements while interacting the environment. How the CNS faces the complexity of control problem and solves the question of physiological and mechanical abundances is not still clear. Modular control is one of the most prevalent hypotheses in answer to these questions. According to this point of view, CNS combines a few building blocks, here this will be muscle activities, named as muscle synergies, to present a vast repertoires of movements. In this study the algorithm of sample-based nonnegative matrix tri-factorization (NM3F) is used to extract spatial and temporal muscle synergy modules from muscle EMG data for three different types of point to point reaching (simple straight, reversal and via-point) movement in the frontal and sagittal planes. After extracting different features of the muscle synergies, physiological interpretation of these decomposed parts has been discussed. The first temporal module coded the direction and type of movement, while the spatial modules describe some via postures. Also the extracted modules are not similar for subjects. The recruitment of the spatial and temporal modules are correlated due to the movement direction.
Volume 13, Issue 3 (1-2023)
Abstract
Background:
HIV has at least six regulatory genes among which the Vif protein can control HIV replication. This study, as the first report, investigated the important mutations in VIF protein in sequences from Iranian patients and using immunoinformatics, conserved regions of this protein and B-Cell, T-Cell and CTL epitopes to stimulate the immune system, were determined.
Methods:
VIF sequences were obtained from NCBI GenBank, and tertiary structures, B-Cell, T-Cell and CTL epitopes were predicted by bioinformatics tools; besides, their antigenic and allergenic properties were studied.
Results:
The most prevalent mutations in Vif protein were related to S 49 P (90%), S 140 N and N 186 S (80%). Two substitutions at positions 41 and 42 were introduced which have effect on Vif binding to host factor. In addition, three regions were identified as the best epitope sequences with high potential to induce immune system and the lowest allergic properties, among which 5-32 region was suggested as the best vaccine candidate regions.
Conclusion:
This study as the first study from Iran using immunoinformatics tools to introduced a region with the high potential to induce humoral and cellular immune systems and lowest allergenic properties which can be used for further studies on HIV vaccines.