Abrasion in pipelines and fluid transfer equipment along with impurities in oil and gas and other industrial processes is one of the most important problems of oil, gas and petrochemical industries. Repair of this equipment is considered as one of the major challenges in industry. Wearing was created by the impact of solid particles with gas and liquid particles or by the collision of liquid droplets with the inner wall of the fluid passageway. This research aims to examine the factors affecting the rate of vane wearing including circulation speed of compressor vane, size of particles within methane, density of particles in compounds, angle of incidence and target metal stiffness. To obtain and analyze the rate of vanes' wearing, degraded pieces of vanes' substance were provided and were used as specimen according to the operational conditions, exploitation, and transfer of gas. During the experimental steps, the rate of wearing with varying conditions in solution and solid particles' compounds was measured. According to the results, the speed rate of circulation of centrifugal compressor impeller is an important parameter in increasing efficiency. To obtain this parameter, the mechanical and metallurgical properties of the compressors should have a good quality. Also, considering the relationship with a parabola form, the abrasion increases with increasing the density of particle. The results of the research were compared to the existing standards and theories and the approaches were presented to decrease degradation and wearing in centrifugal compressors' vanes.