In flows with high Reynolds inside the U-shaped tubes separation phenomenon occurs in the curvature of tubes that causing pressure loss and in conditions associate with heat transfer causes undesirable increase surface temperature in that region. Due to reduced heat transfer rate from surface to fluid temperature increase occurs that in industrial applications in addition to reduce heat transfer causes damage to surface pipes. in the present study, elimination of the separation zone through body force created by plasma actuators and because it reduce the maximum temperature occurred in this region and changes the Peclet number is simulation in this region. For this purpose, the plasma actuators 5kV, 12kV and 19kV with square voltage function inside U-shaped tube in the three streams with Reynolds 3000, 4500 and 6000 have been placed to Influence of actuators on separation control and maximum temperature occurred at this point be investigated. Calculations with using of proposed model of Suzen with time-dependent numerical procedure has been done. And results during time performance of 0 to 50 have been reported. The results shows that maximum surface temperature that occurs in the region of separation in the presence of plasma actuator near this region has a significant reduction that is due to the elimination and change separation region.