"DEFORM" three-dimensional finite element software is used to describe the behavior of plastic deformation of Ti-6Al-4V workpiece during blade preform extrusion process. Under different conditions of extrusion, numerical analysis of the process force parameter during extrusion process is presented. The relative effects of billet temperature, friction coefficient and die temperature on process force were investigated. To determine the process friction coefficient, the ring compression test of Ti-6Al-4V alloy with glass lubrication was performed. Also experimental tests were successfully done in order to manufacture blade preform. It was observed that billet temperature has much effect on force of Ti-6Al-4V alloy blade preform extrusion process. Die temperature has effect on the process force but its effect is not as much as the effect of the billet temperature. By increasing of the die temperature, the process force decreases. Experimental tests showed that the billet transfer process from the furnace to die has important effect on done or not done of the extrusion process because the billet transfer process from the furnace to die is cause of alters the billet initial temperature just before extrusion process. By reducing of the placing and transfer time of billet from the furnace to die, due to the vicinity of the billet and air, billet temperature have less reduction and therefore it becomes easier to shape. Also by increasing the friction coefficient, the force required for extrusion of Ti-6Al-4V alloy blades preform increased.