Nowadays, movement of micro/nano particles has been attracted considerable attention to manufacturing different devices in micro/nano scale and medical and biological applications. Atomic Force Microscope Probe is widely being used for precise small scale movements. During nano-manipulation, micro/nano particles can be moved to a desired destination with high accuracy using Atomic Force Microscope while in contact mode with precise probe control. In this article, by selecting a proper amount of torque applied to the probe tip, deviation from the center and movement of probe have been investigated to assure the contact between the probe and micro/nano particle. Different liquid environments (water, alcohol, and plasma) with different micro/nano particles including biological and non-biological have been used for this investigation. In addition, using sliding mode control, Atomic Force Microscope Probe was used in different environments such as water, alcohol, and plasma. Obtained results showed that the time needed to control different micro/nano particles in plasma was shorter than that of in water; also the time needed in water was shorter than that of in alcohol.