Explosive welding is used for excellent bonding of similar and dissimilar materials with the wide variety of thicknesses,area dimensions and different thermal and mechanical properties. In this study, an Al/St/Al multilayer sheet was fabricated by explosive welding process and the effects of annealing temperature on the interfacial properties of explosively bonded Al/Cu bimetal have been investigated. For this purpose, hardness changes along the thickness of the samples have been measured, and the thickness and type of intermetallic compounds formed at the joining interface have been explored by means of optical microscopy (OM), scanning electron microscopy (SEM) and also energy dispersive spectroscopy (EDS). By heat treatment of the samples at 300, 350 and 400°C, it was observed that intermetallic layer was formed at the interfaces. The obtained results indicate that, with the increase of the annealing temperature, the thickness of intermetallic compounds has increased and the amount of hardness along the thickness of the joining interface has diminished. In the annealed sample at 300 °C for 60 min, it was observed that intermetallic layers have formed at the interface of Al/St bimetals. These layers consist of the intermetallic compound Al2Fe and its thickness gets to about 35 μm at some points.